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Indications/Uses

Gastroesophageal Reflux Disease (GERD):treatment of erosive reflux esophagitis; long-term management of patients with healed esophagitis to prevent relapse; symptomatic treatment of gastroesophageal reflux disease (GERD).Nexium:Tablet:Esomeprazole (NEXIUM) tablets are indicated for:Patients requiring continued non-steroidal anti-inflammatory (NSAID) therapy:treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) therapy; healing of gastric ulcers associated with non-steroidal anti-inflammatory drug (NSAID) therapy, including COX-2 selective NSAIDs; prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug (NSAID) therapy, including COX-2 selective NSAIDs, in patients at risk.Patients requiring continued low dose aspirin (75-325 mg) therapy:prevention of gastric and/or duodenal ulcers associated with low dose aspirin therapy, in patients at risk.Following treatment with Esomeprazole (NEXIUM) IV: Maintenance of hemostasis and prevention of rebleeding of gastric or duodenal ulcers.In combination with an appropriate antibacterial therapeutic regimen for the eradication ofHelicobacter pyloriand; healing ofassociated duodenal ulcer and; prevention of relapse of peptic ulcers in patients withassociated ulcers.Pathological hypersecretory conditions including Zollinger-Ellison syndrome and idiopathic hypersecretion.Granules:Esomeprazole (NEXIUM) oral suspension is primarily indicated for GERD in children 1-12 years old. Esomeprazole (NEXIUM) oral suspension may also be used by patients having difficulty swallowing dispersed Esomeprazole (NEXIUM) tablets. For indications in patients from the age of 12 years reference is made to the Esomeprazole (NEXIUM) Tablet Prescribing Information.Nexium IV:Esomeprazole (NEXIUM) I. V. is indicated as an alternative where oral therapy is not appropriate. I. therapy would constitute only part of a full treatment period for the following indications:Adults:for healing of gastric ulcers associated with NSAID therapy; for prevention of gastric and duodenal ulcers associated with NSAID therapy, in patients at risk. is indicated for the short-term maintenance of hemostasis and prevention of rebleeding in patients following therapeutic endoscopy for acute bleeding gastric or duodenal ulcers.Children and adolescents aged 1-18 years:gastric antisecretory treatment when the oral route is not possible, such as: gastroesophageal reflux disease (GERD) in patients with erosive reflux esophagitis and/or severe symptoms of reflux.

Dosage/Direction for Use

Children 1 - 12 years: Gastroesophageal Reflux Disease (GERD):Treatment of erosive reflux esophagitis: Weight <20 kg: 10 mg once daily for 8 weeks. Weight ≥20 kg: 10 mg or 20 mg once daily for 8 weeks. Long-term management of patients with healed esophagitis to prevent relapse: 10 mg once daily. Symptomatic treatment of gastroesophageal reflux disease (GERD): 10 mg once daily for up to 8 weeks. Doses over 1 mg/kg/day have not been studied.Children 1 - 12 years: Tablets: Gastroesophageal Reflux Disease (GERD): Treatment of erosive reflux esophagitis: 10 mg or 20 mg once daily for 8 weeks. Weight >20 kg: 10 mg or 20 mg once daily for 8 weeks.

Overview

Nexium 24HR Once Daily Dosing Tablets provide lasting relief from frequent heartburn and acid reflux.

Nexium 24HR 20mg esomeprazole tablets are for the lasting symptomatic relief of frequent heartburn, acid regurgitation and other symptoms associated with gastro-oesophageal reflux

Carefully read the enclosed Consumer Medicine Information before use.

AUST R NUMBER:

231439

Ingredients

CONTAINS:

Lactose

INGREDIENTS:

Each tablet contains: Esomeprazole 20mg (as Magnesium Trihydrate).

Safety

PRODUCT WARNINGS:

Do not use:- for children under 18 years of age.- if allergic to esomeprazole.- if allergic to any other proton pump inhibitor (omeprazole, rabeprazole, lansoprazole, pantoprazole).- if you are taking antiretroviral medicines, such as atazanavir.- if you are taking cilostazol a medicine used to treat pain and/or cramping in the lower leg (or arms) due to inadequate blood flow to the muscles.- if you are breastfeeding or intend to breastfeed.- -f you are experiencing weight loss, persistent regurgitation of food or vomiting, difficulty swallowing or symptoms of gastro-intestinal bleeding, except on medical advice- if you are pregnant or intend to become pregnant except on the advice of a doctor or pharmacist- if the expiry date printed on the pack has passed. Ask your pharmacist or doctor before use if you:- have or ever have had serious liver disease.- are taking digoxin (a medicine used to treat heart problems).- are taking ketoconazole (a medicine used to treat fungal infections)- are taking clopidogrel or warfarin (medicines used to stop the blood clotting)- are taking other medicines regularlyThis preparation is for the relief of minor and temporary ailments and should be used strictly as directed. Do not use for any purpose other than what is specified on the pack, except on doctor's advice. Keep to recommended dose. If an overdose is taken or suspected telephone your doctor or the Poisons Information Centre (Australia 13 11 26, or New Zealand 0800 764 766) or go to the Accident and Emergency department at your nearest hospital. Tell your pharmacist or doctor if you do not feel well, if new or additional symptoms occur while you are taking Nexium 24HR Once Daily Dosing.

ONLINE MANDATORY STATEMENT:

Always read the label and follow the directions for use.

Country of Origin

Puerto Rico, US

Alli - Teh Cusí - Costa Rica

Manufacturer

Centro de Trabás de Productos Nacionales, S. A.

No 11-0214 Loma Linda, IL 60601 USAExpiration dateEXPIRATION date:

15 Mar 2024

SAFETY ADMINISTRATION FOR SUCH MEDICINE:Adverse reactions

Consumer Warning

Do not use:- for children under 18 years of age.- if allergic to esomeprazole.- if allergic to any other proton pump inhibitor (omeprazole, rabeprazole, lansoprazole, pantoprazole).

Introduction to Nexium (Esomeprazole)

Nexium, the brand name for esomeprazole, is a widely used medication for the treatment of various bacterial and parasitic infections, including gastrointestinal infections, respiratory tract infections, and certain eye infections. It is also used to treat the signs and symptoms of gastroesophageal reflux disease (GERD), and for its active ingredient, esomeprazole. This compound belongs to the class of proton pump inhibitors (PPIs), which work by reducing the amount of stomach acid produced by the stomach.

Market Size and Growth

The global market for Nexium, based on revenue from cell and hospital pharmacy pharmacies, research brand and specialty pharmacies, is significant and is expected to reach USD 3.6 billion by 2032.1 The market is driven by several key factors:

  • Current Market Size: The United States, for example, is currently valued at USD 8. VELOF MARKET MANAGER Tablets Size: 14 branded and generic equivalents In the coming years, the global market for Nexium can reach USD 3.37 billion and may grow to USD 6.37 billion in 2029.

  • Regional Dominance: North America, including the United States, is expected to dominate the global market, with a market covering the concentration of formulations in the following regions:

Key Players

The Nexium market is growing driven by various factors, including increasing demand for esomeprazoleblockers (NexBers).2,3

  • Brand Name: Nexium is widely used in the treatment of various bacterial and parasitic infections, including gastrointestinal infections, respiratory tract infections, and eye infections.2,3 One of the main brands is Zydus Pharmaceuticals, which is currently the global number 2 preferred brand on attracts loyal customers.zydusph

Regulatory Approvals

The approval process for Nexium is ongoing, and several regulatory agencies such as the FDA2 and the European Medicines Agency are investigating the use of this medication.2,3 Regulatory requirements and the presence of generic manufacturers are key factors that are aimed at improving market conditions and ensuring supply safety.

Patient Assistance Programs

Some pharmaceutical companies may be able to develop new formulations for the treatment of certain bacterial and parasitic infections, and may be able to offer generic versions of Nexium to help reduce the risk of side effects.2,3 Other pharmaceutical programs such as the RedBox Program are available for the management of certain diseases and conditions, and may help to increase patient compliance and access to treatment.

Precautions

Patients who take Nexium should be counselled on its risks and should not adjust their dosage without consulting with a healthcare professional:

  • Pregnancy and Lactation: Nexium can be unsafe to take during pregnancy or while breastfeeding, and should not be used during pregnancy.2,3 Potential risks to pregnant or breastfeeding women include potential fetal abnormalities, potential for fetal harm, and potential for adverse effects on the baby.

Special Precautions

Special considerations for patients with allergies to esomeprazole include avoiding patients who take esomeprazole, and avoiding patients who take other medications that may interact with esomeprazole:

  • Oily stools: The stools should be immediately emptied through a bowel movement, and patients should be advised to limit their intake of stools to 15 minutes before taking a meal.
  • Gastrointestinal Symptoms: These symptoms may include nausea, vomiting, heartburn, and diarrhea.2,3 It is crucial to consult with a healthcare professional or pharmacist if you have any unusual symptoms and to refrain from taking any medication, including Nexium.

Side Effects

There are various side effects that patients should be aware of while taking esomeprazole, and they should be observed closely:

  • Signs of allergic reaction: Some patients may experience skin rashes or itching with the rash clearing up after using this drug.
  • Signs of abdominal pain or discomfort: Numbness, weakness, or dizziness may occur, and patients should be advised to seek medical attention immediately if these symptoms occur.

Alternate Name:Pharmapure RX Esomep-EZS

Description:Nexium treats gastroesophageal reflux disease (GERD), esophagitis, and stomach ulcers. The generic version of Nexium is esomeprazole magnesium. For a supply of 30 oral tablets of Nexium Delayed-Release Capsules 40 mg is approximately $287. Take advantage of our LowerMyRx discount to receive a typical Nexium discount of up to 80% off of the retail price at participating pharmacies near you.

Dosage Form:Capsule Delayed Release

Administration Route:By mouth

Drug Class:Gastric Acid Secretion Inhibitor, Gastrointestinal Agent

Generic Available:Yes

Strength:20 MG

Warnings:Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, vitamin B12 deficiency, or osteoporosis. This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach) This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Stomach pain, nausea, vomiting, weight loss, bloody or black stools

Food Warnings:Do not use esomeprazole if you are also using medicines that contain rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Atazanavir, cilostazol, diazepam, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea. Diarrhea can occur 2 months or more after you stop taking this medicine., Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.

You could be tellingackworth saving money on prescriptions Without seeing a doctor This medicine is not for and does not have any significant side effects. You may have a low level of folic acid in your body.A pharmacist will be notified by e-mail about the products You can use at home This medicine is not for and does not have any significant side effects. This medicine can affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits.